LipiFlow Thermal Pulsation System

A cleared medical device for Meibomian Gland Dysfunction (MGD) shown to improve gland function.

Lipiflow Hero Image

The LipiFlow® Thermal Pulsation System consists of a Console and a single-use sterile device, known as the Activator, and has a drug-free mechanism of action. Eye care professionals use the LipiFlow System to treat MGD patients in-office with confidence and efficiency.

The Lipiflow System represents more than 10 years of dedicated research and is protected by more than 30 patents. A phased pressure profile with adaptive force equalization and proximal-to-distal peristaltic motion evacuates gland contents as the inner lid is gently heated.

| Patent Information

How The LIPIFLOW System Works

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    The procedure centers around the breakthrough Vector Thermal Pulse Technology™ (VTP)

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    After an initial anesthetic drop, no drugs are required for the procedure

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    The LipiFlow system safely delivers therapeutic energies to the meibomian glands while protecting the delicate structures of the patient’s eye

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    As a result, the obstructed meibum is liquefied and pushed up and out of the gland orifices

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    Contoured design vaults the cornea and protects the eye

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    Heat and pressure are regulated with redundant sensors

The Science Behind LipiFlow

VTP: A Breakthrough Inner Lid Approach

Vectored Thermal Pulse Technology uniquely applies heat and peristaltic motion to the eyelid to remove gland obstructions and stagnant gland content.

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A vaulted design protects the cornea while multi-point sensors monitor and regulate heat and pressure throughout the treatment. This maximizes results and minimizes discomfort. Along with force equalization, the eye is protected from heat and pressure while a nominal therapeutic temperature of 42.5 degrees Celsius is applied directly to the inner eyelid where the glands are located, while protecting the eyelid or delicate structures of the globe.



Proprietary heating technology ensures precise temperature regulation with continuous feedback and consistent heat application to the meibomian glands. The insulated and vaulted design of the Activator protects the cornea from unsafe temperatures.

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Intelligent pressure feedback loop sends pulsed sequences to expel blockages and stagnant material from the gland. The custom pressure sequence maximizes gland clearing while device design protects the eye from unnecessary intraocular pressure.

The LipiFlow Activator


86% of dry eye patients are affected by MGD.1

Safety and Effectiveness

Safety and long-term effectiveness have been demonstrated in peer-reviewed studies.2,3,4


LipiFlow’s mechanism of action provides a drug-free approach.

Lipiflow Videos

* Paid consultant of TearScience, Inc.


1. Lemp, M. A., Crews, L. A., Bron, A. J., Foulks, G. N., & Sullivan, B. D. (2012). Distribution of Aqueous-Deficient and Evaporative Dry Eye in a Clinic-Based Patient Cohort. Cornea, 31(5), 472-478. doi:10.1097/ico.0b013e318225415a

2. Lane SS, DuBiner HB, Epstein RJ, et al. A new system, the LipiFlow, for the treatment of meibomian gland dysfunction. Cornea. 2012; 31(4): 396­.

3. Blackie, CA, Coleman, CA, Holland, EJ. The sustained effect (12 months) of a single-dose vectored thermal pulsation procedure for meibomian gland dysfunction and evaporative dry eye. Clin Ophthalmology. 2016; 10: 1385–1396.

4. Blackie C, Carlson AN, Korb DR. Treatment for meibomian gland dysfunction and dry eye symptoms with a single-dose vectored thermal pulsation: a review. Current Opinion in Ophthalmology. 2015; 26(4):306-13.

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